Chapter 6. Evaluation of Nanotoxicity of Foods and Drugs: Biological Properties of Red Elemental Selenium at Nano Size (Nano-Se) In Vitro and In Vivo

  1. Saura C. Sahu2 and
  2. Daniel A. Casciano3
  1. Jinsong Zhang

Published Online: 18 AUG 2009

DOI: 10.1002/9780470747803.ch6

Nanotoxicity

Nanotoxicity

How to Cite

Zhang, J. (2009) Evaluation of Nanotoxicity of Foods and Drugs: Biological Properties of Red Elemental Selenium at Nano Size (Nano-Se) In Vitro and In Vivo, in Nanotoxicity (eds S. C. Sahu and D. A. Casciano), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747803.ch6

Editor Information

  1. 2

    Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708, USA

  2. 3

    Department for Applied Science, University of Arkansas at Little Rock, Little Rock, AR, USA

Author Information

  1. School of Tea and Food Science, Anhui Agricultural University, Hefe 230036, Anhui, China

Publication History

  1. Published Online: 18 AUG 2009
  2. Published Print: 21 AUG 2009

ISBN Information

Print ISBN: 9780470741375

Online ISBN: 9780470747803

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Keywords:

  • nanotoxicity of food and drug evaluation;
  • biological properties of red elemental selenium at nano size (Nano-Se);
  • sodium selenite, selenomethionine and Se-methylselenocysteine;
  • sodium selenite - preventing selenium deficiency disorders in livestock and humans;
  • molecular mechanism underlying selenium toxicity;
  • sodium selenite and Nano-Se cytotoxic effects;
  • cytotoxic effect of sodium selenite on hepatocytes;
  • selenomethionine in foodstuffs and selenium-enriched yeast;
  • Nano-Se with lower toxicity and chemopreventive effect;
  • Nano-Se - novel selenium source with reduced selenium toxicity risk

Summary

This chapter contains sections titled:

  • Introduction

  • Preparation and Characterization of Nano-Se

  • In Vitro Comparison with Sodium Selenite

  • In Vivo Comparison with Sodium Selenite

  • In Vivo Comparison with Selenomethionine

  • In Vivo Comparison with Se-methylselenocysteine

  • Size Effects of Nano-Se In Vitro and In Vivo

  • Summary

  • Acknowledgements

  • References