Chapter 12. Whole-Cell Oxidations and Dehalogenations

  1. John Whittall15 and
  2. Peter Sutton16
  1. Arshdeep Khare1,
  2. Andrew S. Lamm1,
  3. John P.N. Rosazza1,
  4. Sheng Yuan2,
  5. Yi-Jun Dai2,
  6. Matthias Kittelmann3,
  7. Maria Serrano Correia4,
  8. Anton Kuhn3,
  9. Serge Parel5,
  10. Jürgen Kühnöl5,
  11. Reiner Aichholz6,
  12. Monique Ponelle7,
  13. Oreste Ghisalba8,
  14. Koichi Mitsukura9,
  15. Yoshinori Kondo9,
  16. Toyokazu Yoshida9,
  17. Toru Nagasawa9,
  18. Renata P. Limberger10,
  19. Cleber V. Ursini10,
  20. Paulo J. S. Moran10,
  21. J. Augusto R. Rodrigues10,
  22. Marco Antonio Mirata11,
  23. Jens Schrader11,
  24. Louise C. Nolan12,
  25. Kevin E. O'Connor12,
  26. Katja Buehler13,
  27. Andreas Schmid13,
  28. Takamitsu Utsukihara14 and
  29. C. Akira Horiuchi14

Published Online: 15 DEC 2009

DOI: 10.1002/9780470748589.ch12

Practical Methods for Biocatalysis and Biotransformations

Practical Methods for Biocatalysis and Biotransformations

How to Cite

Khare, A., Lamm, A. S., Rosazza, J. P.N., Yuan, S., Dai, Y.-J., Kittelmann, M., Correia, M. S., Kuhn, A., Parel, S., Kühnöl, J., Aichholz, R., Ponelle, M., Ghisalba, O., Mitsukura, K., Kondo, Y., Yoshida, T., Nagasawa, T., Limberger, R. P., Ursini, C. V., Moran, P. J. S., Rodrigues, J. A. R., Mirata, M. A., Schrader, J., Nolan, L. C., O'Connor, K. E., Buehler, K., Schmid, A., Utsukihara, T. and Horiuchi, C. A. (2009) Whole-Cell Oxidations and Dehalogenations, in Practical Methods for Biocatalysis and Biotransformations (eds J. Whittall and P. Sutton), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470748589.ch12

Editor Information

  1. 15

    Manchester Interdisciplinary Biocentre, University of Manchester, United Kingdom

  2. 16

    GlaxoSmithKline, Synthetic Chemistry, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK

Author Information

  1. 1

    Center for Biocatalysis and Bioprocessing, 2501 Crosspark Road, Suite C100 MTF, University of Iowa, Iowa City, Iowa, IA 52242-5000, USA

  2. 2

    Nanjing Engineering Research Center for microbiology, Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Science, Nanjing Normal University, 1, Wenyuan Rd, Nanjing 210046, PR China

  3. 3

    GDC/PSB/Bioreactions, Novartis Institutes of Biomedical Research (NIBR), Novartis Pharma AG, CH-4002 Basel, Switzerland

  4. 4

    Rua Maria Auxiliadora, n°147, 6°andar porta 3, Bairro do Rosário, P-2750-616 Cascais, Portugal

  5. 5

    Biofocus DPI AG, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland

  6. 6

    Metabolism and Pharmacokinetics, NIBR, Novartis Pharma AG, CH-4002 Basel, Switzerland

  7. 7

    Analytical and Imaging Sciences, NIBR, Novartis Pharma AG, CH-4002 Basel, Switzerland

  8. 8

    Ghisalba Life Sciences GmbH, Habshagstrasse 8c, CH-4153 Reinach, Switzerland

  9. 9

    Department of Biomolecular Science, Gifu University, Yanagido 1-1, Gifu 501-1193, Japan

  10. 10

    State University of Campinas, Institute of Chemistry, CP 6154, 13084-971, Campinas-SP, Brazil

  11. 11

    DECHEMA e.V., Karl-Winnacker-Institut, Biochemical Engineering Group, Theodor-Heuss-Allee 25, 60486 Frankfurt, Germany

  12. 12

    School of Biomolecular and Biomedical Science, Conway Institute for Biomolecular and Biomedical Research, National University of Ireland, University College Dublin, Ardmore House, Belfield, Dublin 4, Republic of Ireland

  13. 13

    Laboratory of Chemical Biotechnology, Faculty of Biochemical and Chemical Engineering, TU Dortmund, Emil-Figge-Strasse 66, 44221 Dortmund, Germany

  14. 14

    Department of Chemistry, Rikkyo (St. Paul's) University, Nishi-Ikebukuro, Toshima-Ku, Tokyo 171-8501, Japan

Publication History

  1. Published Online: 15 DEC 2009
  2. Published Print: 18 DEC 2009

ISBN Information

Print ISBN: 9780470519271

Online ISBN: 9780470748589

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Keywords:

  • whole-cell oxidations and dehalogenations;
  • cultivation of S. griseus NRRL 8090;
  • synthesis of 4-hydroxy-1-tetralone;
  • biotransformations of naphthalene to 4-hydroxy-1-tetralone;
  • cultivation of S. maltophilia CGMCC 1.1788;
  • synthesis of 5-hydroxy IMI;
  • biocatalytic synthesis of 6-hydroxy fluvastatin;
  • gas flow in biowave reactor under oxygen supplementation;
  • hydroxylation of adamantane using streptomyces cells;
  • microbial synthesis of organic compounds - preparation of substituted catechols

Summary

This chapter contains sections titled:

  • Biotransformations of Naphthalene to 4-Hydroxy-1-tetralone by Streptomyces griseus NRRL 8090

  • Hydroxylation of Imidacloprid for the Synthesis of Olefin Imidacloprid by Stenotrophomonas maltophilia CGMCC 1.1788

  • Biocatalytic Synthesis of 6-Hydroxy Fluvastatin using Motierella rammaniana DSM 62752 in Shake Flask Culture and on Multi-gram Scale using a Wave Bioreactor

  • Synthesis of 1-Adamantanol from Adamantane through Regioselective Hydroxylation by Streptomyces griseoplanus Cells

  • Enantioselective Benzylic Microbial Hydroxylation of Indan and Tetralin

  • Stereospecific Biotransformation of (R,S)-Linalool by Corynespora cassiicola DSM 62475 into Linalool Oxides

  • The Biocatalytic Synthesis of 4-Fluorocatechol from Fluorobenzene

  • Synthesis of Enantiopure (S)-Styrene Oxide by Selective Oxidation of Styrene by Recombinant Escherichia coli JM101 (pSPZ10)

  • Biotransformation of α-Bromo and α,α′-Dibromo Alkanone into α-Hydroxyketone and α-Diketone by Spirulina platensis