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High-resolution Infrared–Ultraviolet (IR–UV) Double-resonance Spectroscopy of Biological Molecules

  1. E. Cristina Stanca-Kaposta,
  2. John P. Simons

Published Online: 15 SEP 2011

DOI: 10.1002/9780470749593.hrs096

Handbook of High-resolution Spectroscopy

Handbook of High-resolution Spectroscopy

How to Cite

Stanca-Kaposta, E. C. and Simons, J. P. 2011. High-resolution Infrared–Ultraviolet (IR–UV) Double-resonance Spectroscopy of Biological Molecules. Handbook of High-resolution Spectroscopy. .

Author Information

  1. University of Oxford, Chemistry Department, Oxford, UK

Publication History

  1. Published Online: 15 SEP 2011

Abstract

Tunable infrared (IR) laser excitation of small biomolecules entrained in an expanding supersonic jet, or of biomolecular ions held in a cooled ion trap, provides a powerful means of isolating them at low temperatures in the gas phase and probing their vibrational spectroscopy at high resolution. Many alternative experimental strategies have been devised to achieve this. The article reviews their development and presents some representative benchmark examples of their application.

Keywords:

  • vibrational spectroscopy;
  • laser spectroscopy;
  • biomolecules;
  • conformation;
  • protonated ions