Chapter 13. The Pathogenesis and Prevention of Intravascular Catheter-Related Infections

  1. Helen Hamilton CBE, FRCN, RGN Independent nurse consultant2 and
  2. Andrew R. Bodenham FRCA Consultant in Anaesthesia and Intensive Care Medicine3
  1. T. S. J. Elliott BM, BS, BTech, BMedSci, MRCP, FRCPath, PhD, DSc Consultant Microbiologist Director of Acute Medicine Deputy Medical Director

Published Online: 7 MAY 2009

DOI: 10.1002/9780470750186.ch13

Central Venous Catheters

Central Venous Catheters

How to Cite

Elliott, T. S. J. (2009) The Pathogenesis and Prevention of Intravascular Catheter-Related Infections, in Central Venous Catheters (eds H. Hamilton and A. R. Bodenham), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780470750186.ch13

Editor Information

  1. 2

    Intravenous therapy, Oxford Radcliffe Hospitals Trust, Oxfordshire, Oxford, UK

  2. 3

    Leeds General Infirmary, Leeds, UK

Author Information

  1. University Hospital Birmingham NHS Foundation Trust, Selly Oak Hospital, Raddlebarn Road, Selly Oak, Birmingham, UK

Publication History

  1. Published Online: 7 MAY 2009
  2. Published Print: 11 FEB 2009

ISBN Information

Print ISBN: 9780470019948

Online ISBN: 9780470750186



  • catheter-related bloodstream infections;
  • prevention of catheter-related infection;
  • entrapment of microorganisms;
  • gram-negative bacilli;
  • redesigning catheter components;
  • anti-adhesive coatings;
  • needleless intravenous access devices;
  • antimicrobial lock solution;
  • prophylactic thrombolysis


This chapter contains sections titled:

  • Introduction

  • Types of intravascular catheter-related infections

  • Sources of microorganisms resulting in catheter-related infections

  • Development of catheter-related sepsis

  • Causative microorganisms of catheter-related infections

  • Prevention of intravascular catheter-related infections

  • Conclusion

  • References