Chapter 3. The ABO Blood Groups

  1. Geoff Daniels PhD, FRCPath1 and
  2. Imelda Bromilow MSc, CBiol2

Published Online: 30 NOV 2007

DOI: 10.1002/9780470750926.ch3

Essential Guide To Blood Groups

Essential Guide To Blood Groups

How to Cite

Daniels, G. and Bromilow, I. (eds) (2007) The ABO Blood Groups, in Essential Guide To Blood Groups, Blackwell Publishing Ltd, Malden, MA, USA. doi: 10.1002/9780470750926.ch3

Editor Information

  1. 1

    Bristol Institute for Transfusion Sciences, Senior Research Fellow and Head of Molecular Diagnostics, National Blood Service, Bristol, UK

  2. 2

    DiaMed AG, Scientific Manager, Cressier-sur-Morat, Switzerland

Publication History

  1. Published Online: 30 NOV 2007
  2. Published Print: 1 JAN 2007

ISBN Information

Print ISBN: 9781405153492

Online ISBN: 9780470750926



  • ABO blood groups;
  • ABO antigens;
  • ABO antibodies;
  • ABH secretion;
  • H-deficient red cells


This chapter contains section titled:

  • Introduction

  • ABO antigens, antibodies, and inheritance

  • A1 and A2

  • Antigen, phenotype, and gene frequencies

  • ABO antibodies

  • The importance of the ABO system to transfusion and transplantation medicine

  • The biochemical nature of the ABO antigens

  • Biosynthesis of the ABO antigens and ABO molecular genetics

  • H, the precursor of A and B

  • ABH secretion

  • H-deficient red cells

  • Further complexities

  • Acquired changes

  • Associations with disease and functional aspects