Chapter 6. Clinical Significance of Blood Group Antibodies

  1. Geoff Daniels PhD, FRCPath1 and
  2. Imelda Bromilow MSc, CBiol2

Published Online: 30 NOV 2007

DOI: 10.1002/9780470750926.ch6

Essential Guide To Blood Groups

Essential Guide To Blood Groups

How to Cite

Daniels, G. and Bromilow, I. (eds) (2007) Clinical Significance of Blood Group Antibodies, in Essential Guide To Blood Groups, Blackwell Publishing Ltd, Malden, MA, USA. doi: 10.1002/9780470750926.ch6

Editor Information

  1. 1

    Bristol Institute for Transfusion Sciences, Senior Research Fellow and Head of Molecular Diagnostics, National Blood Service, Bristol, UK

  2. 2

    DiaMed AG, Scientific Manager, Cressier-sur-Morat, Switzerland

Publication History

  1. Published Online: 30 NOV 2007
  2. Published Print: 1 JAN 2007

ISBN Information

Print ISBN: 9781405153492

Online ISBN: 9780470750926



  • blood group antibodies;
  • antibody production;
  • clinical significance of antibodies;
  • haemolytic transfusion reactions;
  • intravascular red cell destruction


This chapter contains section titled:

  • Antibody production and structure

  • Factors affecting the clinical significance of antibodies

  • Haemolytic transfusion reactions

  • Haemolytic disease of the fetus and newborn

  • Autoantibodies

  • Tests to assess the potential significance of an antibody

  • Decision-making for transfusion