Chapter 7. What is the Best Strategy for the Management of Hereditary Colorectal Cancer?

  1. John H. Scholefield1,
  2. Axel Grothey2,
  3. Herand Abcarian3 and
  4. Tim Maughan4
  1. Seung-Yong Jeong,
  2. David Chessin,
  3. Susan Ritchie,
  4. John H. Scholefield and
  5. José G. Guillem

Published Online: 14 JAN 2008

DOI: 10.1002/9780470753231.ch7

Challenges in Colorectal Cancer

Challenges in Colorectal Cancer

How to Cite

Jeong, S.-Y., Chessin, D., Ritchie, S., Scholefield, J. H. and Guillem, J. G. (2006) What is the Best Strategy for the Management of Hereditary Colorectal Cancer?, in Challenges in Colorectal Cancer (eds J. H. Scholefield, A. Grothey, H. Abcarian and T. Maughan), Blackwell Publishing Ltd, Malden, Massachusetts, USA. doi: 10.1002/9780470753231.ch7

Editor Information

  1. 1

    Professor of Surgery, University Hospital, Nottingham, UK

  2. 2

    Professor, Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA

  3. 3

    Turi Josefsen Professor and Chairman, Department of Surgery, University of Illinois College of Medicine, Chicago, Illinois, USA

  4. 4

    Professor of Cancer Studies, University of Cardiff, Cardiff, UK

Publication History

  1. Published Online: 14 JAN 2008
  2. Published Print: 1 JAN 2006

ISBN Information

Print ISBN: 9781405127066

Online ISBN: 9780470753231



  • hereditary;
  • colorectal cancer;
  • germline mutations;
  • pigments;
  • proctocolectomy


This chapter contains section titled:

  • Introduction

  • Familial adenomatous polyposis

  • Hereditary non-polyposis colorectal cancer

  • Peutz-Jeghers syndrome (PJS)

  • Juvenile polyposis syndrome (JPS)

  • MYH polyposis

  • Average- (low) and moderate-risk groups

  • Moderate-risk group

  • Genetic testing?

  • Management and surveillance

  • Evaluation

  • Average- (low) risk group

  • Population screening

  • Summary