Chapter 2. Dynamics of Cytoskeletal and Contractile Protein Organization: An Emerging Paradigm for Airway Smooth Muscle Contraction

  1. Kian Fan Chung
  1. Wenwu Zhang and
  2. Susan J. Gunst

Published Online: 4 JUN 2008

DOI: 10.1002/9780470754221.ch2

Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology

Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology

How to Cite

Zhang, W. and Gunst, S. J. (2008) Dynamics of Cytoskeletal and Contractile Protein Organization: An Emerging Paradigm for Airway Smooth Muscle Contraction, in Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology (ed K. F. Chung), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470754221.ch2

Editor Information

  1. Airway Disease Section, National Heart & Lung Institute, Imperial College London, Dovehouse Street, London SW3 6LY, UK

Author Information

  1. Department of Cellular & Integrative Physiology, Indiana University, School of Medicine, 635 Barnhill Drive – MS 313, Indianapolis, IN 46202-5120, USA

Publication History

  1. Published Online: 4 JUN 2008
  2. Published Print: 18 APR 2008

ISBN Information

Print ISBN: 9780470060667

Online ISBN: 9780470754221

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Keywords:

  • cytoskeletal dynamics and contractile protein organization;
  • contractile filament system;
  • smooth muscle contraction and cytoskeletal reorganization;
  • airway smooth muscle regulation paradigm;
  • smooth muscle myosin heavy chain isoform;
  • actomyosin cross-bridge interaction;
  • airway disorder implication;
  • airway smooth muscle mechanical oscillation

Summary

This chapter contains sections titled:

  • Introduction

  • Molecular structure and organization of contractile and cytoskeletal filaments in the airway smooth muscle cell

  • Cytoskeletal dynamics and airway smooth muscle contraction

  • References