Chapter 7. Airway Smooth Muscle Interaction with Mast Cells

  1. Kian Fan Chung
  1. Roger Marthan Professor Staff specialist1,2,3,
  2. Patrick Berger1,2,3,
  3. Pierre-Olivier Girodet1,2,3 and
  4. J. Manuel Tunon-de-Lara1,2,3

Published Online: 4 JUN 2008

DOI: 10.1002/9780470754221.ch7

Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology

Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology

How to Cite

Marthan, R., Berger, P., Girodet, P.-O. and Tunon-de-Lara, J. M. (2008) Airway Smooth Muscle Interaction with Mast Cells, in Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology (ed K. F. Chung), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470754221.ch7

Editor Information

  1. Airway Disease Section, National Heart & Lung Institute, Imperial College London, Dovehouse Street, London SW3 6LY, UK

Author Information

  1. 1

    Laboratoire de Physiologie Cellulaire Respiratoire, Université Bordeaux 2, 146 rue Léo Saignat, F-33076 Bordeaux Cedex, France

  2. 2

    INSERM, U 885, F-33076 Bordeaux, France

  3. 3

    CHU de Bordeaux, Hôpital du Haut-Lévêque, Pôle Cardio-Thoracique, F-33604 Pessac, France

Publication History

  1. Published Online: 4 JUN 2008
  2. Published Print: 18 APR 2008

ISBN Information

Print ISBN: 9780470060667

Online ISBN: 9780470754221

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Keywords:

  • mast tissue-resident cells;
  • mast cell airway smooth muscle interaction;
  • cysteinyl-leukotrienes - potent bronchoconstrictors;
  • signal transducer and transcription 6 (STAT-6) activator;
  • mast cell chemotaxis smooth muscle cell;
  • tumour suppressor in lung cancer-1 (TSLC-1);
  • asthmatic airway smooth muscle layer;
  • mast cell myositis - innovative asthma therapeutic target

Summary

This chapter contains sections titled:

  • Introduction

  • Mast cell mediators alter smooth muscle function

  • Smooth muscle cells induce mast cell chemotaxis

  • Mast cells can adhere to airway smooth muscle

  • Conclusion

  • Acknowledgements

  • References