Chapter 22. Airway Epithelial Defence, Repair and Regeneration

  1. Robert A. Stockley Professor1,
  2. Stephen I. Rennard Professor2,
  3. Klaus Rabe Professor3 and
  4. Bartolome Celli Professor4
  1. Christelle Coraux,
  2. Jean-Marie Tournier,
  3. Jean-Marie Zahm and
  4. Edith Puchelle

Published Online: 11 JAN 2008

DOI: 10.1002/9780470755976.ch22

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

How to Cite

Stockley, R. A., Rennard, S. I., Rabe, K. and Celli, B. (2007) Airway Epithelial Defence, Repair and Regeneration, in Chronic Obstructive Pulmonary Disease, Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470755976.ch22

Author Information

  1. 1

    Professor of Medicine, Department of Medicine, Queen Elizabeth Hospital, Birmingham, B15 2TH, UK

  2. 2

    Pulmonary & Critical Care Medicine Section, University of Nebraska Medical Center, 985125 Nebraska Medical Center, 800 South 42nd Street, Omaha, NE 68198-5300

  3. 3

    Dept of Pulmonology, Leiden Universtiy Medical Centre, Albinusdreef 2, C3-P, Postbox 9600, 2300 RC, Leiden, Netherlands

  4. 4

    Division of Pulmonary and Critical Care, St Elizabeth's Medical Centre, 736 Cambridge Street, Tufts University, Boston, MA 02135-2907

Publication History

  1. Published Online: 11 JAN 2008
  2. Published Print: 1 JAN 2007

ISBN Information

Print ISBN: 9781405122894

Online ISBN: 9780470755976



  • airway epithelium;
  • pseudomonas aeruginosa;
  • regeneration;
  • airway xenografts;
  • progenitor cells


This chapter contains sections titled:

  • Airway epithelial cells: mechanisms of defence and injury

  • In vivo and in vitro models of airway epithelial repair and regeneration

  • Cellular and molecular mechanisms of airway epithelial repair and regeneration

  • Airway stem cells and progenitor cells

  • Strategies for future therapy of airway cytoprotection, repair and regeneration

  • References