Chapter 32. Oxidants

  1. Robert A. Stockley Professor1,
  2. Stephen I. Rennard Professor2,
  3. Klaus Rabe Professor3 and
  4. Bartolome Celli Professor4
  1. William MacNee

Published Online: 11 JAN 2008

DOI: 10.1002/9780470755976.ch32

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

How to Cite

Stockley, R. A., Rennard, S. I., Rabe, K. and Celli, B. (2007) Oxidants, in Chronic Obstructive Pulmonary Disease, Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470755976.ch32

Author Information

  1. 1

    Professor of Medicine, Department of Medicine, Queen Elizabeth Hospital, Birmingham, B15 2TH, UK

  2. 2

    Pulmonary & Critical Care Medicine Section, University of Nebraska Medical Center, 985125 Nebraska Medical Center, 800 South 42nd Street, Omaha, NE 68198-5300

  3. 3

    Dept of Pulmonology, Leiden Universtiy Medical Centre, Albinusdreef 2, C3-P, Postbox 9600, 2300 RC, Leiden, Netherlands

  4. 4

    Division of Pulmonary and Critical Care, St Elizabeth's Medical Centre, 736 Cambridge Street, Tufts University, Boston, MA 02135-2907

Publication History

  1. Published Online: 11 JAN 2008
  2. Published Print: 1 JAN 2007

ISBN Information

Print ISBN: 9781405122894

Online ISBN: 9780470755976

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Keywords:

  • oxidative stress;
  • gene expression;
  • cell-derived oxidants;
  • hydrogen peroxide;
  • muscle dysfunction

Summary

This chapter contains sections titled:

  • Oxidative stress

  • Mucus hypersecretion

  • Oxidative stress and muscle dysfunction

  • Inflammation, oxidative stress and gene expression

  • Oxidative stress and the development of airways obstruction

  • Therapy to be targeted at oxidative stress

  • Future perspectives

  • References