19. Protein Cages as Multimode Imaging Agents

  1. Xiaoyuan Chen2,3
  1. Masaki Uchida,
  2. Lars Liepold,
  3. Mark Young and
  4. Trevor Douglas

Published Online: 25 MAY 2011

DOI: 10.1002/9780470767047.ch19

Nanoplatform-Based Molecular Imaging

Nanoplatform-Based Molecular Imaging

How to Cite

Uchida, M., Liepold, L., Young, M. and Douglas, T. (2011) Protein Cages as Multimode Imaging Agents, in Nanoplatform-Based Molecular Imaging (ed X. Chen), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470767047.ch19

Editor Information

  1. 2

    Molecular Imaging Program at Stanford and Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA

  2. 3

    Laboratory for Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA

Author Information

  1. Department of Chemistry and Biochemistry and Department of Plant Science, Center for Bio-Inspired Nanomaterials, Montana State University, Bozeman, Montana, USA

Publication History

  1. Published Online: 25 MAY 2011
  2. Published Print: 28 MAR 2011

ISBN Information

Print ISBN: 9780470521151

Online ISBN: 9780470767047



  • protein cages as multimode imaging agents, and library of protein cages - supporting synthetic chemistries and genetic manipulations, creating high performance multimode imaging agents;
  • protein cages as T1 agents, and Gd agents - enhancing T1 relaxation process and “T1” to a time in units of seconds, equal to a realignment decay constant for proton's spin;
  • protein cages, as contrast agents - imaging atherosclerotic plaques


This chapter contains sections titled:

  • Introduction

  • Protein Cage Based Magnetic Materials as MRI Contrast Agents

  • Protein Cages as T1 Agents

  • Protein Cages as T2 MRI Contrast Agents

  • Protein Cages as Contrast Agents for Imaging Atherosclerotic Plaques

  • Protein Cages as Vehicles for Targeted Delivery of Imaging Agents to Biofilm Infections

  • Conclusion

  • References