Chapter 26. Genetic Epidemiology of Type 1 Diabetes Mellitus

  1. Dr Jean-Marie Ekoé Professor of Medicine Faculty of Medicine member recipient principal investigator co-investigator Chairman3,
  2. Dr Marian Rewers principal investigator Core director Program Chair Chair4,
  3. Rhys Williams Dean of Medicine Professor of Clinical Epidemiology chair Vice President Editor-in-Chief member visiting consultant5 and
  4. Paul Zimmet Director Hon. Professor Officer6
  1. Kirsten O. Kyvik1 and
  2. Anders Green2

Published Online: 11 SEP 2008

DOI: 10.1002/9780470779750.ch26

The Epidemiology of Diabetes Mellitus, Second Edition

The Epidemiology of Diabetes Mellitus, Second Edition

How to Cite

Kyvik, K. O. and Green, A. (2008) Genetic Epidemiology of Type 1 Diabetes Mellitus, in The Epidemiology of Diabetes Mellitus, Second Edition (eds J.-M. Ekoé, M. Rewers, R. Williams and P. Zimmet), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470779750.ch26

Editor Information

  1. 3

    Endocrinologie, Métabolisme et Nutrition, Centre de Recherche du CHUM, Montreal, Canada

  2. 4

    Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO, USA

  3. 5

    Clinical Epidemiology at the School of Medicine, University of Swansea, Swansea, UK

  4. 6

    International Diabetes Institute Caulfield, Victoria, Australia

Author Information

  1. 1

    Institute of Regional Health Services Research and Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark

  2. 2

    Department of Research and Applied, Health Technology Assessment, Odense, University Hospital and Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark

Publication History

  1. Published Online: 11 SEP 2008
  2. Published Print: 19 SEP 2008

ISBN Information

Print ISBN: 9780470017272

Online ISBN: 9780470779750

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Keywords:

  • genetic epidemiology - etiology, distribution and disease control;
  • type 1 diabetes mellitus - genetic epidemiology;
  • type 1 diabetes - etiology and pathogenesis;
  • test performance measures;
  • type 1 diabetes - predicting risk;
  • reduced first-phase insulin response and intravenous glucose challenge;
  • immune markers and immune system activation;
  • type 1 diabetes immune markers - islet-cell antibodies (ICAs)

Summary

This chapter contains sections titled:

  • Introduction

  • Evidence of a Genetic Contribution to Type 1 Diabetes

  • Evidence of Environmental Determinants

  • Predicting Risk of Type 1 Diabetes: Available Markers

  • Predicting Risk of Type 1 Diabetes: Methodological Considerations

  • Predicting Risk of Type 1 Diabetes: A Hyphothetical Example

  • Concluding Remarks

  • References