10. Advanced Methods for Analysing Quality of Life Outcomes

  1. Stephen J. Walters

Published Online: 10 SEP 2009

DOI: 10.1002/9780470840481.ch10

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation

How to Cite

Walters, S. J. (2009) Advanced Methods for Analysing Quality of Life Outcomes, in Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470840481.ch10

Author Information

  1. School of Health and Related Research, University of Sheffield, UK

Publication History

  1. Published Online: 10 SEP 2009
  2. Published Print: 25 SEP 2009

ISBN Information

Print ISBN: 9780470753828

Online ISBN: 9780470686140

SEARCH

Keywords:

  • bootstrap method for estimating confidence intervals;
  • QoL measured or scored on ordered categorical (ordinal) scale;
  • non-parametric Mann–Whitney U-test;
  • bootstrap - computer-intensive method for statistical analysis;
  • bootstrap methods for confidence interval estimation;
  • mean QoL from bootstrap replications;
  • bias-corrected method and bias-corrected and accelerated (BCa) method;
  • STATA and S-PLUS - built-in procedures bootstrapping and estimating bootstrap CIs;
  • QoL scales - continuous for statistical analysis purposes;
  • proportional odds or cumulative logit model

Summary

This chapter contains sections titled:

  • Summary

  • Introduction

  • Bootstrap methods

  • Bootstrap methods for confidence interval estimation

  • Ordinal regression

  • Comparing two independent groups: Ordinal quality of life measures (with less than 7 categories)

  • Proportional odds or cumulative logit model

  • Continuation ratio model

  • Stereotype logistic model

  • Conclusions and further reading