13. Practical Issues
Published Online: 10 SEP 2009
DOI: 10.1002/9780470840481.ch13
Copyright © 2009 John Wiley & Sons, Ltd
Book Title
Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation
Additional Information
How to Cite
Walters, S. J. (2009) Practical Issues, in Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470840481.ch13
Publication History
- Published Online: 10 SEP 2009
- Published Print: 25 SEP 2009
Book Series:
ISBN Information
Print ISBN: 9780470753828
Online ISBN: 9780470686140
- Summary
- Chapter
Keywords:
- practical issues in analysing studies using QoL outcomes;
- US Food and Drug Administration (FDA) draft guidance for using QoL outcomes;
- missing data proportion and its importance;
- missing forms - more serious than missing items;
- last observation carried forward (LOCF);
- regression imputation of missing forms;
- PONDER study - cluster randomized controlled trial (cRCT) in primary care;
- EPDS, Edinburgh Postnatal Depression Scale;
- simpler univariate approach and each individual QoL dimension;
- quality of life outcome measures in clinical trials
Summary
This chapter contains sections titled:
Summary
Missing data
Multiplicity, multi-dimensionality and multiple quality of life outcomes
Guidelines for reporting quality of life studies