9. Exploring and Modelling Longitudinal Quality of Life Data

  1. Stephen J. Walters

Published Online: 10 SEP 2009

DOI: 10.1002/9780470840481.ch9

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation

How to Cite

Walters, S. J. (2009) Exploring and Modelling Longitudinal Quality of Life Data, in Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation: A Practical Guide to Analysis and Interpretation, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470840481.ch9

Author Information

  1. School of Health and Related Research, University of Sheffield, UK

Publication History

  1. Published Online: 10 SEP 2009
  2. Published Print: 25 SEP 2009

ISBN Information

Print ISBN: 9780470753828

Online ISBN: 9780470686140

SEARCH

Keywords:

  • randomized controlled trial and baseline QoL assessment;
  • repeated measures ANOVA, marginal general linear models (GLMs), and random-effect (multi-level) GLMs;
  • time-by-time analysis;
  • response feature analysis and use of summary measures;
  • analysis of covariance (ANCOVA) - preferred method of choice;
  • Area under the curve (AUC) - repeated QoL scores as single measure of health;
  • longitudinal data modelling;
  • postnatal depression (PND) in new mothers;
  • Postnatal Depression Randomized Controlled Trial and Economic Evaluation (PONDER) RCT;
  • mean EPDS score for individual mothers

Summary

This chapter contains sections titled:

  • Summary

  • Introduction

  • Summarizing, tabulating and graphically displaying repeated QoL assessments

  • Time-by-time analysis

  • Response feature analysis – the use of summary measures

  • Modelling of longitudinal data

  • Conclusions