Chapter 1. Introduction to the Discipline of Toxicology

  1. Helmut Greim M.D.1 and
  2. Robert Snyder Ph.D. Associate Dean for Research Professor of Pharmacology and Toxicology2
  1. Helmut Greim M.D.1 and
  2. Robert Snyder Ph.D. Associate Dean for Research Professor of Pharmacology and Toxicology2

Published Online: 8 FEB 2008

DOI: 10.1002/9780470868959.ch1

Toxicology and Risk Assessment: A Comprehensive Introduction

Toxicology and Risk Assessment: A Comprehensive Introduction

How to Cite

Greim, H. and Snyder, R. (2008) Introduction to the Discipline of Toxicology, in Toxicology and Risk Assessment: A Comprehensive Introduction (eds H. Greim and R. Snyder), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470868959.ch1

Editor Information

  1. 1

    Institut für Toxikologie und Umwelthygiene, Technische Universität München, Germany

  2. 2

    Ernest Mario School of Pharmacy and the Environmental and Occupational Health Sciences Institute, Rutgers the State University of New Jersey, Piscataway, USA

Author Information

  1. 1

    Institut für Toxikologie und Umwelthygiene, Technische Universität München, Germany

  2. 2

    Ernest Mario School of Pharmacy and the Environmental and Occupational Health Sciences Institute, Rutgers the State University of New Jersey, Piscataway, USA

Publication History

  1. Published Online: 8 FEB 2008
  2. Published Print: 25 JAN 2008

ISBN Information

Print ISBN: 9780470868935

Online ISBN: 9780470868959

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Keywords:

  • no-observable-effect level (NOEL);
  • persistent accumulated damage;
  • dose–response relationship;
  • oral cavity and gastrointestinal tract;
  • tumor-suppressor genes and apoptosis;
  • single occluded patch;
  • phototoxicity and photoallergic reactions;
  • enterohepatic circulation;
  • gap–junction-mediated intercellular communication;
  • occupational exposure standards

Summary

This chapter contains sections titled:

  • Introduction

  • The Risk-Assessment Process

  • Toxicological Evaluation of New and Existing Chemicals

  • Summary

  • References

  • For Further Reading