Chapter 6. Toxicity of Selected Chemicals

  1. Helmut Greim M.D.11 and
  2. Robert Snyder Ph.D. Associate Dean for Research Professor of Pharmacology and Toxicology12
  1. Kristian W. Fried1,
  2. Karl K. Rozman1,
  3. Karl-Heinz Summer2,
  4. Stefan Halbach2,
  5. Herrmann Kappus3,
  6. Helmut Greim M.D.11,
  7. Paul J. A. Borm4,
  8. Gisela H. Degen5,
  9. J. William Owens6,
  10. Wolfgang Dekant7,
  11. Marion W. Anders8,
  12. Ladislaus Szinicz9 and
  13. Thomas Zilker10

Published Online: 8 FEB 2008

DOI: 10.1002/9780470868959.ch6

Toxicology and Risk Assessment: A Comprehensive Introduction

Toxicology and Risk Assessment: A Comprehensive Introduction

How to Cite

Fried, K. W., Rozman, K. K., Summer, K.-H., Halbach, S., Kappus, H., Greim, H., Borm, P. J. A., Degen, G. H., Owens, J. W., Dekant, W., Anders, M. W., Szinicz, L. and Zilker, T. (2008) Toxicity of Selected Chemicals, in Toxicology and Risk Assessment: A Comprehensive Introduction (eds H. Greim and R. Snyder), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470868959.ch6

Editor Information

  1. 11

    Institut für Toxikologie und Umwelthygiene, Technische Universität München, Germany

  2. 12

    Ernest Mario School of Pharmacy and the Environmental and Occupational Health Sciences Institute, Rutgers the State University of New Jersey, Piscataway, USA

Author Information

  1. 1

    Deptartment of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, USA

  2. 2

    Institut für Toxikologie, GSF-Forschungszentrum für Umwelt & Gesundheit, Neuherberg, Germany

  3. 3

    Klinik für Dermatologie, Charite, Campus Virchow-Klinikum, Berlin, Germany

  4. 4

    Centre of Expertise in Life Sciences, Zuyd University, Heerlen, The Netherlands

  5. 5

    Institut für Arbeitsphysiologie an der Universität Dortmund, Germany

  6. 6

    The Procter and Gamble Company, Central Product Safety, Cincinnati, Ohio, USA

  7. 7

    Institut für Pharmakologie und Toxikologie der Universität Würzburg, Germany

  8. 8

    Department of Pharmacology, University of Rochester, NY, USA

  9. 9

    Institut für Pharmakologie und Toxikologie, Sanitätsakademie der Bundeswehr, München, Germany

  10. 10

    Toxikologische Abteilung der II. Medizinischen Klinik und Poliklinik Rechts der Isar der Technischen Universität München, Germany

  11. 11

    Institut für Toxikologie und Umwelthygiene, Technische Universität München, Germany

Publication History

  1. Published Online: 8 FEB 2008
  2. Published Print: 25 JAN 2008

ISBN Information

Print ISBN: 9780470868935

Online ISBN: 9780470868959



  • cumulative worldwide production;
  • lipid peroxidation and mitochondrial dysfunction;
  • hemolytic anemia and hemoglobinuria;
  • water-soluble chromates and dichromates;
  • bronchoalveolar lavage fluid (BAL);
  • endogenous steroid hormones;
  • biotransformation-dependent toxicities;
  • fluorinated resins and paint;
  • physiologically important mediator;
  • ovine-derived fragment antigen binding (Fab) fragments


This chapter contains sections titled:

  • Persistent Polyhalogenated Aromatic Hydrocarbons

  • Metals

  • Toxicology of Fibers and Particles

  • Xenoestrogens and Xenoantiandrogens

  • Toxicology of Solvents

  • Noxious Gases

  • Animal and Plant Toxins

  • References

  • For Further Reading

  • Further Reading

  • Reference