14. Techniques for Prioritization of Candidate Disease Genes

  1. Ujjwal Maulik2,
  2. Sanghamitra Bandyopadhyay3 and
  3. Jason T. L. Wang4
  1. Jieun Jeong and
  2. Jake Y. Chen

Published Online: 25 AUG 2010

DOI: 10.1002/9780470872352.ch14

Computational Intelligence and Pattern Analysis in Biological Informatics

Computational Intelligence and Pattern Analysis in Biological Informatics

How to Cite

Jeong, J. and Chen, J. Y. (2010) Techniques for Prioritization of Candidate Disease Genes, in Computational Intelligence and Pattern Analysis in Biological Informatics (eds U. Maulik, S. Bandyopadhyay and J. T. L. Wang), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470872352.ch14

Editor Information

  1. 2

    Department of Computer Science and Engineering, Jadavpur University, Kolkata, India

  2. 3

    Machine Intelligence Unit, Indian Statistical Institute, Kolkata, India

  3. 4

    Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA

Author Information

  1. School of Informatics, Indiana University-Purdue University, Indianapolis, Indiana, USA

Publication History

  1. Published Online: 25 AUG 2010
  2. Published Print: 11 OCT 2010

ISBN Information

Print ISBN: 9780470581599

Online ISBN: 9780470872352

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Keywords:

  • systems biology - techniques for candidate disease gene prioritization;
  • prioritization based on text-mining - with reference to phenotypes;
  • prioritization based on joint use of interaction network

Summary

This chapter contains sections titled:

  • Introduction

  • Prioritization Based on Text-Mining with Reference to Phenotypes

  • Prioritization with No Direct Reference to Phenotypes

  • Prioritization Using Interaction Networks

  • Prioritization Based on Joint Use of Interaction Network and Literature-Based Similarity Between Phenotypes

  • Fusion of Data from Multiple Sources

  • Conclusions and Open Problems

  • Acknowledgment

  • References