Chapter 14. Endolysosomolytically Active pH-Sensitive Polymeric Nanotechnology

  1. Volkmar Weissig2 and
  2. Gerard G. M. D'Souza3
  1. Han Chang Kang and
  2. You Han Bae

Published Online: 25 AUG 2010

DOI: 10.1002/9780470875780.ch14

Organelle-Specific Pharmaceutical Nanotechnology

Organelle-Specific Pharmaceutical Nanotechnology

How to Cite

Kang, H. C. and Bae, Y. H. (2010) Endolysosomolytically Active pH-Sensitive Polymeric Nanotechnology, in Organelle-Specific Pharmaceutical Nanotechnology (eds V. Weissig and G. G. M. D'Souza), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470875780.ch14

Editor Information

  1. 2

    Department of Pharmaceutical Sciences, Midwestern University College of Pharmacy, Glendale, Arizona, USA

  2. 3

    Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences, Boston, Massachusetts, USA

Author Information

  1. Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah, USA

Publication History

  1. Published Online: 25 AUG 2010
  2. Published Print: 11 OCT 2010

ISBN Information

Print ISBN: 9780470631652

Online ISBN: 9780470875780



  • endolysosomolytically active pH-sensitive polymeric nanotechnology;
  • site-specific nanotherapeutics;
  • endolysosomolytic polymeric gene nanocomplexes


This chapter contains sections titled:

  • Site - Specific Nanotherapeutics

  • Destabilization of Endolysosomal Compartments

  • Endolysosomolytic Polymeric Nanocarriers

  • Conclusion

  • Acknowledgments

  • References