Chapter 17. The Potential of Photochemical Internalization (PCI) for the Cytosolic Delivery of Nanomedicines

  1. Volkmar Weissig3 and
  2. Gerard G. M. D'Souza4
  1. Kristian Berg1,
  2. Anette Weyergang1,
  3. Anders Høgset2 and
  4. Pål Kristian Selbo1

Published Online: 25 AUG 2010

DOI: 10.1002/9780470875780.ch17

Organelle-Specific Pharmaceutical Nanotechnology

Organelle-Specific Pharmaceutical Nanotechnology

How to Cite

Berg, K., Weyergang, A., Høgset, A. and Selbo, P. K. (2010) The Potential of Photochemical Internalization (PCI) for the Cytosolic Delivery of Nanomedicines, in Organelle-Specific Pharmaceutical Nanotechnology (eds V. Weissig and G. G. M. D'Souza), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470875780.ch17

Editor Information

  1. 3

    Department of Pharmaceutical Sciences, Midwestern University College of Pharmacy, Glendale, Arizona, USA

  2. 4

    Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences, Boston, Massachusetts, USA

Author Information

  1. 1

    Department of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Montebello, Oslo, Norway

  2. 2

    PCI Biotech AS, Oslo, Norway

Publication History

  1. Published Online: 25 AUG 2010
  2. Published Print: 11 OCT 2010

ISBN Information

Print ISBN: 9780470631652

Online ISBN: 9780470875780



  • potential of photochemical internalization (PCI) - for nanomedicine cytosolic delivery;
  • PCI for gene delivery gene therapy - novel therapeutic modality receiving much attention;
  • PCI, highly efficient in macromolecule internalization improvement


This chapter contains sections titled:

  • Introduction

  • Photodynamic Therapy

  • Photochemical Internalization (PCI)

  • Conclusion

  • References