Chapter 22. Cell-Penetrating Peptides for Cytosolic Delivery of Biomacromolecules

  1. Volkmar Weissig2 and
  2. Gerard G. M. D'Souza3
  1. Camilla Foged,
  2. Xiaona Jing and
  3. Hanne Moerck Nielsen

Published Online: 25 AUG 2010

DOI: 10.1002/9780470875780.ch22

Organelle-Specific Pharmaceutical Nanotechnology

Organelle-Specific Pharmaceutical Nanotechnology

How to Cite

Foged, C., Jing, X. and Nielsen, H. M. (2010) Cell-Penetrating Peptides for Cytosolic Delivery of Biomacromolecules, in Organelle-Specific Pharmaceutical Nanotechnology (eds V. Weissig and G. G. M. D'Souza), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470875780.ch22

Editor Information

  1. 2

    Department of Pharmaceutical Sciences, Midwestern University College of Pharmacy, Glendale, Arizona, USA

  2. 3

    Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences, Boston, Massachusetts, USA

Author Information

  1. Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark

Publication History

  1. Published Online: 25 AUG 2010
  2. Published Print: 11 OCT 2010

ISBN Information

Print ISBN: 9780470631652

Online ISBN: 9780470875780

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Keywords:

  • cell-penetrating peptides (CPP) for biomacromolecule cytosolic delivery;
  • lipophilic cell membranes, intense interest in elucidating - mechanisms of internalization;
  • design of cell-penetrating peptides - for intracellular cargo delivery

Summary

This chapter contains sections titled:

  • Introduction

  • Internalization Mechanisms and Intracellular Trafficking

  • Design of Cell - Penetrating Peptides for Intracellular Cargo Delivery

  • Methodologies

  • Side Effects

  • Conclusion

  • List of Abbreviations

  • References