3. The Protein Structure Initiative

  1. Huzefa Rangwala5 and
  2. George Karypis6
  1. Andras Fiser1,
  2. Adam Godzik2,
  3. Christine Orengo3 and
  4. Burkhard Rost4

Published Online: 7 SEP 2010

DOI: 10.1002/9780470882207.ch3

Introduction to Protein Structure Prediction: Methods and Algorithms

Introduction to Protein Structure Prediction: Methods and Algorithms

How to Cite

Fiser, A., Godzik, A., Orengo, C. and Rost, B. (2010) The Protein Structure Initiative, in Introduction to Protein Structure Prediction: Methods and Algorithms (eds H. Rangwala and G. Karypis), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470882207.ch3

Editor Information

  1. 5

    Department of Computer Science, George Mason University, Fairfax, VA 22030, USA

  2. 6

    Department of Computer Science, University of Minnesota Minneapolis, MN 55455, USA

Author Information

  1. 1

    Department of Systems and Computational Biology and Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA

  2. 2

    Program in Bioinformatics and Systems Biology, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA

  3. 3

    Department of Structural and Molecular Biology, University College London, London UK

  4. 4

    Department of Biochemistry and Molecular Biophysics, Center for Computational Biology, Columbia University, New York, NY 10032, USA

Publication History

  1. Published Online: 7 SEP 2010
  2. Published Print: 12 NOV 2010

Book Series:

  1. Wiley Series on Bioinformatics: Computational Techniques and Engineering

Book Series Editors:

  1. Yi Pan and
  2. Albert Zomaya

ISBN Information

Print ISBN: 9780470470596

Online ISBN: 9780470882207



  • protein structure initiative (PSI);
  • target selection for large centers in PSI - overseen by BioInformatics Groups (BIG4);
  • dissemination of results of PSI - venues as central gateway, the PSI Structural Genomics Knowledgebase


This chapter contains sections titled:

  • Background, Rationale, and History

  • Overview, Pipeline, and Resources

  • Target Selection and Target Categories

  • Performance of PSI

  • Dissemination of Results

  • Conclusions and Future Perspectives

  • References