4. Genetic Manipulation Methods in Bacillus anthracis

  1. Nicholas H. Bergman
  1. Brian K. Janes1 and
  2. Scott Stibitz2

Published Online: 8 NOV 2010

DOI: 10.1002/9780470891193.ch4

Bacillus anthracis and Anthrax

Bacillus anthracis and Anthrax

How to Cite

Janes, B. K. and Stibitz, S. (2010) Genetic Manipulation Methods in Bacillus anthracis, in Bacillus anthracis and Anthrax (ed N. H. Bergman), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470891193.ch4

Author Information

  1. 1

    Department of Microbiology and Immunology, University of Michigan Medical Center, USA

  2. 2

    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, USA

Publication History

  1. Published Online: 8 NOV 2010
  2. Published Print: 22 NOV 2010

ISBN Information

Print ISBN: 9780470410110

Online ISBN: 9780470891193



  • genetic manipulation methods - in Bacillus anthracis;
  • random insertion of mobile DNA elements - libraries of bacterial mutants, powerful tool in bacterial genetics;
  • allelic exchange, more stable mutations - isolation, using allelic exchange technique


This chapter contains sections titled:

  • Introduction

  • Delivery of Foreign DNA

  • Isolation of Mutants

  • Concluding Remarks

  • References