1. Bioinformatics and Mathematics

  1. Matthew He1 and
  2. Sergey Petoukhov2

Published Online: 12 OCT 2010

DOI: 10.1002/9780470904640.ch1

Mathematics of Bioinformatics: Theory, Practice, and Applications

Mathematics of Bioinformatics: Theory, Practice, and Applications

How to Cite

He, M. and Petoukhov, S. (2010) Bioinformatics and Mathematics, in Mathematics of Bioinformatics: Theory, Practice, and Applications, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470904640.ch1

Author Information

  1. 1

    Nova Southeastern University, Fort Lauderdale, Florida, USA

  2. 2

    Russian Academy of Sciences, Moscow, Russia

Publication History

  1. Published Online: 12 OCT 2010
  2. Published Print: 17 DEC 2010

Book Series:

  1. Bioinformatics: Computational Techniques and Engineering

Book Series Editors:

  1. Yi Pan and
  2. Albert Y. Zomaya

ISBN Information

Print ISBN: 9780470404430

Online ISBN: 9780470904640



  • bioinformatics;
  • genetic code;
  • informatics;
  • mathematics


Traditionally, the study of biology is from morphology to cytology and then to the atomic and molecular level, from physiology to microscopic regulation, and from phenotype to genotype. The recent development of bioinformatics begins with research on genes and moves to the molecular sequence, then to molecular conformation, from structure to function, from systems biology to network biology, and further investigates the interactions and relationships among, genes, proteins, and structures. Mathematics and biological data have a synergistic relationship. This chapter provides an overview of bioinformatics history, genetic code and mathematics, background mathematics for bioinformatics, and the big picture of bioinformatics-informatics. It also provides a general background of major branches of mathematics that is discussed in relation to bioinformatics. Informatics has many aspects and encompasses a number of existing academic disciplines: artificial intelligence, cognitive science, and computer science.

Controlled Vocabulary Terms

artificial intelligence; symbol manipulation