3. Introduction to Biomarkers

  1. Virginia Litwin3,
  2. Philip Marder4
  1. Ole Vesterqvist1,
  2. Manjula P. Reddy2

Published Online: 27 OCT 2010

DOI: 10.1002/9780470910085.ch3

Book Title

Flow Cytometry in Drug Discovery and Development

Flow Cytometry in Drug Discovery and Development

Additional Information

How to Cite

Vesterqvist, O. and Reddy, M. P. (2010) Introduction to Biomarkers, in Flow Cytometry in Drug Discovery and Development (eds V. Litwin and P. Marder), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470910085.ch3

Editor Information

  1. 3

    Covance Central Laboratory Services, Indianapolis, IN, USA

  2. 4

    Redram Consulting, LLC, Indianapolis, IN, USA

Author Information

  1. 1

    Covance Central Laboratory Services Inc., Indianapolis, IN, USA

  2. 2

    Ortho Biotech, Unit of Centocor R&D, Johnson and Johnson, Radnor, PA, USA

Publication History

  1. Published Online: 27 OCT 2010
  2. Published Print: 20 DEC 2010

ISBN Information

Print ISBN: 9780470433560

Online ISBN: 9780470910085

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CHAPTER TOOLS

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Keywords:

  • biomarkers, new biomarkers - and new technologies to measure biomarkers;
  • multiplexed assays, moving toward patient stratification biomarkers - genotyping or gene expression;
  • biomarkers in clinical development - integral part of drug development

Summary

This chapter contains sections titled:

  • Introduction

  • Types of Biomarkers

  • Technology Platforms

  • Biomarkers in Discovery

  • Analytical Validation of Biomarker Assays

  • Biomarker Qualification

  • Biomarker in Clinical Development

  • Conclusions

  • References

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