19. Initial Identification and Confirmation of a QTL Gene

  1. Weikuan Gu3 and
  2. Yongjun Wang4
  1. David C. Airey1 and
  2. Chun Li2

Published Online: 10 FEB 2012

DOI: 10.1002/9780470933947.ch19

Gene Discovery for Disease Models

Gene Discovery for Disease Models

How to Cite

Airey, D. C. and Li, C. (2011) Initial Identification and Confirmation of a QTL Gene, in Gene Discovery for Disease Models (eds W. Gu and Y. Wang), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470933947.ch19

Editor Information

  1. 3

    Department of Orthopedic Surgery—Campbell Clinic, University of Tennessee Health Science Center, Memphis, TN, USA

  2. 4

    Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Author Information

  1. 1

    Department of Pharmacology, Vanderbilt University School of Medicine Nashville, TN, USA

  2. 2

    Department of Biostatistics, Vanderbilt University School of Medicine Nashville, TN, USA

Publication History

  1. Published Online: 10 FEB 2012
  2. Published Print: 21 MAR 2011

ISBN Information

Print ISBN: 9780470499467

Online ISBN: 9780470933947

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Keywords:

  • initial identification and confirmation of QTL gene - quantitative genetics, as studies of biological variation;
  • fine mapping QTL, and selective phenotyping - and recombinant progeny testing localizing QTL;
  • confirmation of a QTL gene - identifying a candidate gene for a mapped QTL

Summary

This chapter contains sections titled:

  • Introduction

  • Initial Mapping of QTL

  • Fine Mapping QTL

  • Confirmation of a QTL Gene

  • Bioinformatics, Systems Genetics, and Networks

  • Pharmacogenomics and Dynamic Phenotyping

  • References