6. Bioinformatics Tools for Gene Function Prediction

  1. Weikuan Gu2 and
  2. Yongjun Wang3
  1. Yan Cui

Published Online: 10 FEB 2012

DOI: 10.1002/9780470933947.ch6

Gene Discovery for Disease Models

Gene Discovery for Disease Models

How to Cite

Cui, Y. (2011) Bioinformatics Tools for Gene Function Prediction, in Gene Discovery for Disease Models (eds W. Gu and Y. Wang), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470933947.ch6

Editor Information

  1. 2

    Department of Orthopedic Surgery—Campbell Clinic, University of Tennessee Health Science Center, Memphis, TN, USA

  2. 3

    Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Author Information

  1. Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, TN, USA

Publication History

  1. Published Online: 10 FEB 2012
  2. Published Print: 21 MAR 2011

ISBN Information

Print ISBN: 9780470499467

Online ISBN: 9780470933947

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Keywords:

  • bioinformatics tools for gene function prediction - in natural languages, difficulty for computers to process;
  • protein structure comparison, detecting remote evolutionary relationships - in absence of sequence similarity;
  • function prediction using integrated data - interacting proteins, forming protein interaction networks

Summary

This chapter contains sections titled:

  • Gene Ontology: Description of Gene Function with Controlled and Structured Vocabulary

  • Sequence-Based Function Prediction

  • Structure-Based Function Prediction

  • Function Prediction Using Integrated Data

  • Questions and Answers

  • References