4. Two-Dimensional Gel Electrophoresis: Basic Principles and Application to Platelet Signaling Studies

  1. Ángel García1 and
  2. Yotis A. Senis2
  1. ángel García

Published Online: 12 JUL 2011

DOI: 10.1002/9780470940297.ch4

Platelet Proteomics: Principles, Analysis, and Applications

Platelet Proteomics: Principles, Analysis, and Applications

How to Cite

García, á. (2011) Two-Dimensional Gel Electrophoresis: Basic Principles and Application to Platelet Signaling Studies, in Platelet Proteomics: Principles, Analysis, and Applications (eds Á. García and Y. A. Senis), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470940297.ch4

Editor Information

  1. 1

    Department of Pharmacology, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela, Spain

  2. 2

    Centre for Cardiovascular Sciences, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

Author Information

  1. Department of Pharmacology, Facultade de Farmacia, Universidade de Santiago de Compostela, Santiago de Compostela, Spain

Publication History

  1. Published Online: 12 JUL 2011
  2. Published Print: 9 MAY 2011

Book Series:

  1. Wiley-Interscience Series in Mass Spectrometry

Book Series Editors:

  1. Dominic M. Desiderio3 and
  2. Nico M. M. Nibbering4

Series Editor Information

  1. 3

    Departments of Neurology and Biochemistry, University of Tennessee Health Science Center, USA

  2. 4

    Vrije Universiteit Amsterdam, The Netherlands

ISBN Information

Print ISBN: 9780470463376

Online ISBN: 9780470940297

SEARCH

Keywords:

  • platelet proteome, global approaches and subproteomes - two-dimensional gel electrophoresis, principles in platelet signaling studies;
  • platelet proteome analysis by 2DGE-based proteomics - and general proteome mapping;
  • high-resolution 2DGE, tool for differential analyses - comparing basal and activated platelets

Summary

This chapter contains sections titled:

  • Introduction: Two-Dimensional Gel Electrophoresis (2DGE) in Proteomics Research

  • Analysis of Platelet Proteome by 2DGE-Based Proteomics

  • Concluding Remarks

  • Acknowledgments

  • References