1. Genomic Variations and Marker Technologies for Genome-Based Selection

  1. Zhanjiang (John) Liu
  1. Zhanjiang (John) Liu

Published Online: 10 DEC 2010

DOI: 10.1002/9780470958964.ch1

Next Generation Sequencing and Whole Genome Selection in Aquaculture

Next Generation Sequencing and Whole Genome Selection in Aquaculture

How to Cite

Liu, Z. (2011) Genomic Variations and Marker Technologies for Genome-Based Selection, in Next Generation Sequencing and Whole Genome Selection in Aquaculture (ed Z. (. Liu), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780470958964.ch1

Editor Information

  1. The Fish Molecular Genetics and Biotechnology Laboratory, Department of Fisheries and Allied Aquacultures and Program of Cell and Molecular Biosciences, Aquatic Genomics Unit, Auburn University, Auburn, AL 36849 USA

Author Information

  1. The Fish Molecular Genetics and Biotechnology Laboratory, Department of Fisheries and Allied Aquacultures and Program of Cell and Molecular Biosciences, Aquatic Genomics Unit, Auburn University, Auburn, AL 36849 USA

Publication History

  1. Published Online: 10 DEC 2010
  2. Published Print: 28 JAN 2011

ISBN Information

Print ISBN: 9780813806372

Online ISBN: 9780470958964

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Keywords:

  • genomic variations and marker technologies - for genome-based selection;
  • genetic variations - at the genomic level;
  • genome compositions, of each individual of same species - similar, and different at level of DNA sequences;
  • genome variations, and wide range of segmental inversions or rearrangements;
  • base substitution along DNA chain - as single-nucleotide polymorphisms (SNPs);
  • CNV in teleost fish, additional round of genome duplication - and random gene loss;
  • DNA marker technologies, revealing DNA-level differences of genomes - among individuals of same species, and related taxa;
  • molecular markers, and protein- and DNA markers - overcoming problems associated with phenotypic markers;
  • Restriction Fragment Length Polymorphism (RFLP);
  • Random Amplified Polymorphic DNA (RAPD) markers - RAPD, multilocus DNA fingerprinting technique using PCR, amplifying nuclear DNA with single short PCR primer

Summary

This chapter contains sections titled:

  • Genetic Variations at the Genomic Level

  • A Review of DNA Marker Technologies

  • Trend of DNA Marker Technologies

  • Assessment of the Usefulness of Various Markers for Genome - based Selection

  • Acknowledgments

  • References