17. The Effect of Maternal Macronutrient Intake on Phenotype Induction and Epigenetic Gene Regulation

  1. Mihai D. Niculescu3 and
  2. Paul Haggarty4
  1. Karen A. Lillycrop1,
  2. Mark A. Hanson2 and
  3. Graham C. Burdge2

Published Online: 13 APR 2011

DOI: 10.1002/9780470959824.ch17

Nutrition in Epigenetics

Nutrition in Epigenetics

How to Cite

Lillycrop, K. A., Hanson, M. A. and Burdge, G. C. (2011) The Effect of Maternal Macronutrient Intake on Phenotype Induction and Epigenetic Gene Regulation, in Nutrition in Epigenetics (eds M. D. Niculescu and P. Haggarty), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780470959824.ch17

Editor Information

  1. 3

    Department of Nutrition and Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA

  2. 4

    Nutrition & Epigenetics Group, Rowett Institute of Nutrition & Health, University of Aberdeen, Aberdeen, Scotland, UK

Author Information

  1. 1

    School of Biological Sciences, University of Southampton, Southampton, UK

  2. 2

    DOHaD Research Division, University of Southampton, Southampton, UK

Publication History

  1. Published Online: 13 APR 2011
  2. Published Print: 27 MAY 2011

ISBN Information

Print ISBN: 9780813816050

Online ISBN: 9780470959824

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Keywords:

  • maternal nutrition;
  • phenotype induction;
  • glucocorticoid receptor (GR);
  • Global Dietary Restriction;
  • Prenatal Nutrition

Summary

This chapter contains sections titled:

  • Introduction

  • Maternal Nutrition and Phenotype Induction

  • Phenotype Inductionl and Altered Transcription

  • Epigenetic Mechanisms and Regulation of Transcription

  • Environmental Challenge in Early Life and Epigenetic Regulation of Imprinted Genes

  • Prenatal Nutrition and Altered Epigenetic Gene Regulation

  • Transgenerational Transmission of Altered Epigenetic Gene Regulation

  • Reversal or Prevention of Altered Phenotype and Epigenotype

  • Mechanisms for Induced Changes in the Epigenome

  • Conclusion

  • References