12. Animal Parasitology and Proteomics

  1. P. David Eckersall1 and
  2. Phillip D. Whitfield2
  1. Richard Burchmore

Published Online: 5 AUG 2011

DOI: 10.1002/9780470960660.ch12

Methods in Animal Proteomics

Methods in Animal Proteomics

How to Cite

Burchmore, R. (2011) Animal Parasitology and Proteomics, in Methods in Animal Proteomics (eds P. D. Eckersall and P. D. Whitfield), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780470960660.ch12

Editor Information

  1. 1

    University of Glasgow, UK

  2. 2

    University of the Highlands and Islands, UK

Author Information

  1. University of Glasgow, UK

Publication History

  1. Published Online: 5 AUG 2011
  2. Published Print: 19 AUG 2011

ISBN Information

Print ISBN: 9780813817910

Online ISBN: 9780470960660

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Keywords:

  • animal parasitology and proteomics - proteome, protein complement of biological system;
  • proteomic technologies, context of animal parasitology - opportunities and challenges;
  • proteomic technologies - sensitivity and speed improvements, key developments;
  • proteomic analysis of parasites - restricted by limited parasite genome sequence information;
  • axenic culture systems - in enabling experiments, not capable of being carried out using animal models;
  • subproteomic analysis, and proteins - host–parasite interface, Schistosoma Bovis recovered;
  • proteomic analysis of in vivo parasites - proteomic analysis, of complete host parasite system;
  • proteomic approaches, in identifying vaccine targets - for animal parasite control;
  • drug action and resistance understanding - chemotherapy, in parasitic disease control, drug development and serendipity;
  • parasitic infection diagnosis - comparative proteomics and metabolomics, revealing protein and small molecule biomarkers as diagnostics

Summary

This chapter contains sections titled:

  • Introduction

  • Proteomic Technologies

  • Parasite Proteomics

  • The Potential of Comparative Proteomic Analysis

  • Understanding Drug Action and Resistance

  • Downstream of the Proteome: Metabolomics

  • Global Approaches and the Search for Biomarkers

  • Future Trends

  • Reference