7. Advancing Technologies for Spatial and Temporal Proteomics

  1. P. David Eckersall1 and
  2. Phillip D. Whitfield2
  1. Mary Doherty

Published Online: 5 AUG 2011

DOI: 10.1002/9780470960660.ch7

Methods in Animal Proteomics

Methods in Animal Proteomics

How to Cite

Doherty, M. (2011) Advancing Technologies for Spatial and Temporal Proteomics, in Methods in Animal Proteomics (eds P. D. Eckersall and P. D. Whitfield), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780470960660.ch7

Editor Information

  1. 1

    University of Glasgow, UK

  2. 2

    University of the Highlands and Islands, UK

Author Information

  1. University of the Highlands and Islands, UK

Publication History

  1. Published Online: 5 AUG 2011
  2. Published Print: 19 AUG 2011

ISBN Information

Print ISBN: 9780813817910

Online ISBN: 9780470960660

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Keywords:

  • advancing technologies for spatial and temporal proteomics - link between expressed genes and phenotypic outcomes;
  • spatial proteomics, location of proteins - within a cell, three-dimensional shape of a protein;
  • moving from a static “snap-shot” of system - to dynamic processes, sophisticated analytical and bioinformatics resources;
  • spatial proteome, fundamental goals - of biological research, understanding protein relationship in complex organisms;
  • proteomics, defining performance characteristics of muscle;
  • fractions, analyzed by 1DGE - and Western blotting, mitochondria enriched three-to-fourfold;
  • temporal proteomics - and temporal fluctuations, resulting from development;
  • protein abundance modulation - mediated by posttranscriptional control of translation, or protein PTM and degradation;
  • combining spatial and temporal proteomics - proteomic approach, studying chicken cardiovascular system;
  • animal proteomics, expanding field - new opportunities, for understanding basic biology

Summary

This chapter contains sections titled:

  • Introduction

  • Investigating the Spatial Proteome

  • Temporal Proteomics

  • Case Study: Spatial and Temporal Profiling in the Chicken

  • Combining Spatial and Temporal Proteomics

  • Recent Developments in Animal Proteomics

  • Future Trends

  • Conclusions

  • Sources of Further Information

  • References