3. The Association Between Depression and Heart Disease: The Role of Genetic Factors

  1. Alexander Glassman2,3,
  2. Mario Maj4 and
  3. Norman Sartorius5
  1. Eco de Geus

Published Online: 14 NOV 2010

DOI: 10.1002/9780470972304.ch3

Depression and Heart Disease

Depression and Heart Disease

How to Cite

de Geus, E. (2010) The Association Between Depression and Heart Disease: The Role of Genetic Factors, in Depression and Heart Disease (eds A. Glassman, M. Maj and N. Sartorius), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470972304.ch3

Editor Information

  1. 2

    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, New York, NY, USA

  2. 3

    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY, USA

  3. 4

    Department of Psychiatry, University of Naples SUN, Naples, Italy

  4. 5

    Association for the Improvement of Mental Health Programmes, Geneva, Switzerland

Author Information

  1. Department of Biological Psychology, VU University, Amsterdam, The Netherlands

Publication History

  1. Published Online: 14 NOV 2010
  2. Published Print: 5 NOV 2010

ISBN Information

Print ISBN: 9780470710579

Online ISBN: 9780470972304



  • Genetic Association Studies;
  • major depressive disorder (MDD);
  • Heritability of CAD and CAD Risk Factors;
  • sudden cardiac death (SCD);
  • coronary flow reserve (CFR);
  • myocardial infarction (MI);
  • Center for Epidemiology Studies Depression Scale (CES-D);
  • white blood cell count (WBC);
  • tumour necrosis factor (TNF);
  • genome-wide association (GWA)


This chapter contains sections titled:

  • Twin Studies

  • Genetic Association Studies

  • Concluding Remarks

  • References