16. Non-Substrate-Directed Partial Epilepsy

  1. Gregory D. Cascino MD, FAAN4,5 and
  2. Joseph I. Sirven MD4,6,7
  1. Korwyn Williams1,2 and
  2. Katherine H. Noe MD, PhD3,4

Published Online: 18 MAR 2011

DOI: 10.1002/9780470975039.ch16

Adult Epilepsy

Adult Epilepsy

How to Cite

Williams, K. and Noe, K. H. (2011) Non-Substrate-Directed Partial Epilepsy, in Adult Epilepsy (eds G. D. Cascino and J. I. Sirven), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470975039.ch16

Editor Information

  1. 4

    Mayo Clinic College of Medicine, USA

  2. 5

    Division of Epilepsy, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA

  3. 6

    Mayo Clinic Arizona, USA

  4. 7

    Department of Neurology, Division of Epilepsy, Mayo Clinic Hospital, 5 East, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA

Author Information

  1. 1

    Department of Pediatrics, University of Arizona College of Medicine, Phoenix, AZ 85004, USA

  2. 2

    Division of Neurology Children's, Neuroscience Institute, Phoenix Children's Hospital, Phoenix, AZ 85004, USA

  3. 3

    Department of Neurology, Division of Epilepsy, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA

  4. 4

    Mayo Clinic College of Medicine, USA

Publication History

  1. Published Online: 18 MAR 2011
  2. Published Print: 8 APR 2011

ISBN Information

Print ISBN: 9780470741221

Online ISBN: 9780470975039

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Keywords:

  • non-substrate-directed partial epilepsy;
  • partial epilepsy, and underlying CNS structural lesion or disorders;
  • classification of seizure type and epilepsy syndrome - determining prognosis and treatment;
  • seizures in two-thirds of those with epilepsy - well controlled with medical therapy;
  • genetic, or IPE syndromes - idiopathic focal epilepsies, demonstrating complex inheritance patterns, with mutifactorial genetic and environmental influences;
  • medically refractory epilepsy, and good surgical outcome - structural abnormality detection, with complete resection;
  • selected idiopathic partial epilepsy syndromes;
  • positron emission tomography (PET) - noninvasive technology, for cerebral metabolism evaluation using different ligands;
  • localization-related epilepsy - more common than generalized epilepsy, prognosis for seizure control and remission variable;
  • MRI lesion resection, and postoperative seizure freedom - in about seventy percent of refractory epilepsy patients

Summary

This chapter contains sections titled:

  • Introduction

  • Genetic or IPE syndromes

  • Medically refractory non-substrate-directed partial epilepsy

  • Conclusions

  • References