8. Clinical Utility of Clozapine in Bipolar Disorder

  1. Hagop S. Akiskal4 and
  2. Mauricio Tohen5
  1. V. E. Cosgrove1,3,
  2. J. S. Seo2,3,
  3. H. Yang1,3 and
  4. Trisha Suppes1,3

Published Online: 13 APR 2011

DOI: 10.1002/9780470975114.ch8

Bipolar Psychopharmacotherapy: Caring for the Patient, Second Edition

Bipolar Psychopharmacotherapy: Caring for the Patient, Second Edition

How to Cite

Cosgrove, V. E., Seo, J. S., Yang, H. and Suppes, T. (2011) Clinical Utility of Clozapine in Bipolar Disorder, in Bipolar Psychopharmacotherapy: Caring for the Patient, Second Edition (eds H. S. Akiskal and M. Tohen), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470975114.ch8

Editor Information

  1. 4

    International Mood Center, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0603, USA

  2. 5

    Department of Psychiatry, Division of Mood and Anxiety Disorders, University of Texas Health Science Centre at San Antonio, 7730 Floyd Curl Drive, San Antonio, TX 78229, USA

Author Information

  1. 1

    Stanford School of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA

  2. 2

    Stanford School of Medicine, Stanford University Medical Center, 291 Campus Drive MC 5216, Stanford, CA 94305-5101, CA, USA

  3. 3

    VA Palo Alto Health Care System, Palo Alto, CA, USA

Publication History

  1. Published Online: 13 APR 2011
  2. Published Print: 15 APR 2011

ISBN Information

Print ISBN: 9780470747216

Online ISBN: 9780470975114

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Keywords:

  • Clinical Utility of Clozapine in Bipolar Disorder;
  • Food and Drug Administration (FDA);
  • Pharmacokinetics;
  • Clozaril National Registry (CNR);
  • white blood count (WBC);
  • Myocarditis;
  • Clinical Global Impressions (CGI)

Summary

This chapter contains sections titled:

  • Introduction

  • History

  • Clinical pharmacology of clozapine

  • Clozapine in bipolar disorders

  • Effective pharmacotherapy for bipolar disorder?

  • Case studies

  • References