16. Epidemiology of Schizophrenia

  1. Ming T. Tsuang4,5,
  2. Mauricio Tohen6,7 and
  3. Peter B. Jones8
  1. William W. Eaton1,
  2. Chuan-Yu Chen2 and
  3. Evelyn J. Bromet3

Published Online: 19 APR 2011

DOI: 10.1002/9780470976739.ch16

Textbook of Psychiatric Epidemiology, Third Edition

Textbook of Psychiatric Epidemiology, Third Edition

How to Cite

Eaton, W. W., Chen, C.-Y. and Bromet, E. J. (2011) Epidemiology of Schizophrenia, in Textbook of Psychiatric Epidemiology, Third Edition (eds M. T. Tsuang, M. Tohen and P. B. Jones), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470976739.ch16

Editor Information

  1. 4

    Center for Behavioral Genomics, Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla CA 92039, USA

  2. 5

    Harvard Institute of Psychiatric Epidemiology & Genetics, Harvard School of Public Health, Boston, USA

  3. 6

    Department of Psychiatry, University of Texas Health Science Centre at San Antonio, USA

  4. 7

    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7526 Louis Pasteur Drive, San Antonio TX 78229-3900, USA

  5. 8

    Department of Psychiatry, University of Cambridge, Box 189, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK

Author Information

  1. 1

    Dept of Mental Health, Bloomberg School of Public Health, John Hopkins School of Hygiene and Public Health, John Hopkins University, 615 N. Wolfe Street, Baltimore MD 21205, USA

  2. 2

    National Health Research Institutes, Institute of Population Health Sciences, Division of Mental Health and Addiction Medicine, Taiwan

  3. 3

    Dept of Psychiatry, SUNY Stony Brook University, PutnamHall – South Campus, Stony Brook NY 11794-8790, USA

Publication History

  1. Published Online: 19 APR 2011
  2. Published Print: 15 APR 2011

ISBN Information

Print ISBN: 9780470694671

Online ISBN: 9780470976739



  • epidemiology of schizophrenia;
  • psychotic disorders - schizophrenia, being debilitating and persistent;
  • research on schizophrenia - integrating suggestions from key studies and reviews;
  • clinical diagnoses, basis of epidemiological studies - and case registries;
  • clinical cohort studies - diagnoses derived from semi-structured examinations, as Present State Examination (PSE) and Schedules for Clinical Assessment in Neuropsychiatry (SCAN);
  • WHO followup of schizophrenia - after 5 years;
  • demographic correlates - age and sex, force of morbidity of schizophrenia peaks in young adulthood;
  • social risk factors, and ethnicity - ethnic status, shared history with others;
  • biological risk factors and genes;
  • results, linking schizophrenia to autoimmune disease - clinical and laboratory study of autoimmune processes in schizophrenia


This chapter contains sections titled:

  • Introduction

  • Methods

  • The burden of schizophrenia

  • Natural history

  • Demographic correlates

  • Social risk factors

  • Biological risk factors

  • Prevention

  • Discussion

  • References