Chapter 13. Pharmacokinetic/Pharmacodynamic Factors and Steroid Sensitivity

  1. Ian M. Adcock and
  2. Kian Fan Chung
  1. Gönther Hochhaus

Published Online: 18 MAR 2008

DOI: 10.1002/9780470985731.ch13

Overcoming Steroid Insensitivity in Respiratory Disease

Overcoming Steroid Insensitivity in Respiratory Disease

How to Cite

Hochhaus, G. (2008) Pharmacokinetic/Pharmacodynamic Factors and Steroid Sensitivity, in Overcoming Steroid Insensitivity in Respiratory Disease (eds I. M. Adcock and K. F. Chung), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470985731.ch13

Editor Information

  1. Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK

Author Information

  1. College of Pharmacy, University of Florida, Gainsville, FL, USA

Publication History

  1. Published Online: 18 MAR 2008
  2. Published Print: 14 MAR 2008

ISBN Information

Print ISBN: 9780470058084

Online ISBN: 9780470985731

SEARCH

Keywords:

  • pulmonary inflammation;
  • pharmacokinetic/pharmacodynamic (PK/PD) relationships;
  • drug molecules;
  • performance of inhaled glucocorticoids;
  • oral bioavailability

Summary

This chapter contains sections titled:

  • Introduction

  • What factors are important for pulmonary efficacy and safety?

  • Pharmacodynamic aspects

  • Pharmacokinetic drug properties

  • Conclusion

  • References