Chapter 3. Glucocorticoid Receptor Subtypes and Steroid Sensitivity

  1. Ian M. Adcock and
  2. Kian Fan Chung
  1. Robert H. Oakley and
  2. John A. Cidlowski

Published Online: 18 MAR 2008

DOI: 10.1002/9780470985731.ch3

Overcoming Steroid Insensitivity in Respiratory Disease

Overcoming Steroid Insensitivity in Respiratory Disease

How to Cite

Oakley, R. H. and Cidlowski, J. A. (2008) Glucocorticoid Receptor Subtypes and Steroid Sensitivity, in Overcoming Steroid Insensitivity in Respiratory Disease (eds I. M. Adcock and K. F. Chung), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470985731.ch3

Editor Information

  1. Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK

Author Information

  1. Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, MD F307, Research Triangle Park, NC, USA

Publication History

  1. Published Online: 18 MAR 2008
  2. Published Print: 14 MAR 2008

ISBN Information

Print ISBN: 9780470058084

Online ISBN: 9780470985731

SEARCH

Keywords:

  • Glucocorticoids are endogenous hormones;
  • glucocorticoid receptor (GR);
  • physiological and pathophysiological conditions;
  • one-gene–one-receptor paradigm;
  • amino-terminal transactivation domain

Summary

This chapter contains sections titled:

  • Introduction

  • Overview of classic GR function

  • GR subtypes arising from alternative splicing

  • GR subtypes arising from alternative translation initiation

  • Conclusions

  • References