Chapter 6. Corticosteroid Responsiveness in Asthma: Clinical Aspects
- Ian M. Adcock,
- Kian Fan Chung
Published Online: 18 MAR 2008
DOI: 10.1002/9780470985731.ch6
Copyright © 2008 John Wiley & Sons, Ltd
Book Title
Overcoming Steroid Insensitivity in Respiratory Disease
Additional Information
How to Cite
Chung, K. F. (2008) Corticosteroid Responsiveness in Asthma: Clinical Aspects, in Overcoming Steroid Insensitivity in Respiratory Disease (eds I. M. Adcock and K. F. Chung), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470985731.ch6
Editor Information
Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK
Publication History
- Published Online: 18 MAR 2008
- Published Print: 14 MAR 2008
ISBN Information
Print ISBN: 9780470058084
Online ISBN: 9780470985731
- Summary
- Chapter
Keywords:
- introduction of inhaled corticosteroid (ICS) therapy;
- corticosteroid-resistant (CSR) asthma;
- corticosteroid sensitive (CSS);
- glucocorticoid receptor binding;
- peak expiratory flow rate (PEFR)
Summary
This chapter contains sections titled:
Introduction
Effects of corticosteroids in asthma
Definition of corticosteroid insensitivity
Oral CS responsiveness in asthma
ICS responsiveness in asthma
CS responsiveness in severe asthma
Surrogates for CS responsiveness in asthma
Pharmacokinetics of systemic CS in severe asthma
CS responsiveness in cigarette smokers and chronic obstructive pulmonary disease
Other diseases of CS insensitivity
Conclusions
References