Chapter 23. Molecular Genetics of Cardiovascular Disorders

  1. Salim Yusuf1,
  2. John A Cairns2,
  3. A John Camm3,
  4. Ernest L Fallen4 and
  5. Bernard J Gersh5
  1. AJ Marian and
  2. Robert Roberts

Published Online: 4 OCT 2007

DOI: 10.1002/9780470986882.ch23

Evidence-based Cardiology, Second Edition

Evidence-based Cardiology, Second Edition

How to Cite

Marian, A. and Roberts, R. (2002) Molecular Genetics of Cardiovascular Disorders, in Evidence-based Cardiology, Second Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), BMJ Books, London, UK. doi: 10.1002/9780470986882.ch23

Editor Information

  1. 1

    Heart and Stroke Foundation of Ontario Research Chair, Senior Scientist of the Canadian Institute of Health Research, Director of Cardiology and Professor of Medicine, McMaster, University, Hamilton Health Sciences, Hamilton, Canada

  2. 2

    Dean, Faculty of Medicine, University of British Columbia, Vancouver, Canada

  3. 3

    Professor of Clinical Cardiology and Chief, Department of Cardiological Sciences, St George's Hospital Medical School, London, UK

  4. 4

    Professor Emeritus, McMaster University, Faculty of Health Sciences, Hamilton, Canada

  5. 5

    Consultant in Cardiovascular Diseases and Internal Medicine, Mayo Clinic; Professor of Medicine, Mayo Medical School, Rochester, Minnesota, USA

Publication History

  1. Published Online: 4 OCT 2007
  2. Published Print: 20 NOV 2002

ISBN Information

Print ISBN: 9780727916990

Online ISBN: 9780470986882

SEARCH

Keywords:

  • molecular genetics;
  • cardiovascular disorders;
  • mutations;
  • inheritance patterns;
  • polygenic inheritance

Summary

This chapter contains sections titled:

  • Mutations responsible for single gene disorders

  • Patterns of inheritance of single gene disorders

  • Polygenic inheritance of cardiac disease

  • Family history and inherited cardiovascular disorders

  • Single gene cardiovascular disorders

  • Arrhythmogenic right ventricular dysplasia (ARVD)

  • Genetics and future therapy

  • A diagnostic test for preclinical FHCM derived from genetic animal models