Chapter 28. Primary Biliary Cirrhosis

  1. John WD McDonald1,
  2. Andrew K Burroughs2 and
  3. Brian G Feagan3
  1. Jenny Heathcote

Published Online: 25 OCT 2007

DOI: 10.1002/9780470987025.ch28

Evidence-based Gastroenterology and Hepatology, Second Edition

Evidence-based Gastroenterology and Hepatology, Second Edition

How to Cite

Heathcote, J. (2004) Primary Biliary Cirrhosis, in Evidence-based Gastroenterology and Hepatology, Second Edition (eds J. W. McDonald, A. K. Burroughs and B. G. Feagan), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470987025.ch28

Editor Information

  1. 1

    Professor of Medicine, University of Western Ontario, Gastroenterology Service, London Health Sciences Centre, London, Ontario, Canada

  2. 2

    Consultant Physician/Hepatologist, Royal Free Hospital, London, UK

  3. 3

    Professor of Medicine, University of Western Ontario, Gastroenterology Service, London Health Sciences Centre, London, Ontario, Canada

Publication History

  1. Published Online: 25 OCT 2007
  2. Published Print: 10 NOV 2004

ISBN Information

Print ISBN: 9780727917515

Online ISBN: 9780470987025

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Keywords:

  • primary biliary cirrhosis;
  • progressive fibrosis;
  • liver transplantation;
  • autoimmune disease;
  • hydrophilic bile acids

Summary

This chapter contains sections titled:

  • Introduction

  • Diagnosis

  • Natural history

  • Surrogate markers of outcome

  • Timing for liver transplantation

  • Therapeutic trial design: assessment of credibility

  • Randomized controlled trials of treatment for primary biliary cirrhosis

  • The future for primary biliary cirrhosis