Chapter 23. Physiology of Reperfusion Injury

  1. Rodney A. White MD1,
  2. Larry H. Hollier MD2
  1. Shervanthi Homer-Vanniasinkam,
  2. D. Neil Granger

Published Online: 4 OCT 2007

DOI: 10.1002/9780470987094.ch23

Book Title

Vascular Surgery: Basic Science and Clinical Correlations, Second Edition

Vascular Surgery: Basic Science and Clinical Correlations, Second Edition

Additional Information

How to Cite

Homer-Vanniasinkam, S. and Granger, D. N. (2007) Physiology of Reperfusion Injury, in Vascular Surgery: Basic Science and Clinical Correlations, Second Edition (eds R. A. White and L. H. Hollier), Blackwell Publishing, Malden, Massachusetts, USA. doi: 10.1002/9780470987094.ch23

Editor Information

  1. 1

    Professor of Surgery, UCLA School of Medicine, Chief, Division of Vascular Surgery, Harbor-UCLA Medical Center, Torrance, California

  2. 2

    Dean, Louisiana State University School of Medicine in New Orleans, New Orleans, Louisiana

Publication History

  1. Published Online: 4 OCT 2007
  2. Published Print: 15 MAR 2005

ISBN Information

Print ISBN: 9781405122023

Online ISBN: 9780470987094

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CHAPTER TOOLS

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Keywords:

  • revascularization;
  • xanthine oxidase;
  • reperfusion injury;
  • nitric oxide;
  • Ischemia-Reperfusion

Summary

This chapter contains sections titled:

  • Parenchymal cell changes

  • Partial and total ischemia

  • Role of reactive oxygen metabolites

  • Xanthine oxidase

  • Leukocyte-endothelial cell adhesion in reperfusion injury

  • Platelet-endothelial cell adhesion

  • Nitric oxide

  • Clinical manifestations of I/R injury

  • Conclusions

  • Acknowledgment

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