Chapter 15. Molecular Variations in the Core Promoter, Precore and Core Regions of Hepatitis B Virus, and their Clinical Significance

  1. Howard Thomas BSc PhD FRCP FRCpath FMedSci Professor1,
  2. Stanley Lemon Professor2 and
  3. Arie Zuckerman MD, DSc, FRCP, FRCPath, FMedSci, Dip. Bact Professor3
  1. Peter Karayiannis,
  2. William F Carman and
  3. Howard C Thomas

Published Online: 26 OCT 2007

DOI: 10.1002/9780470987131.ch15

Viral Hepatitis, Third Edition

Viral Hepatitis, Third Edition

How to Cite

Karayiannis, P., Carman, W. F. and Thomas, H. C. (2005) Molecular Variations in the Core Promoter, Precore and Core Regions of Hepatitis B Virus, and their Clinical Significance, in Viral Hepatitis, Third Edition (eds H. Thomas, S. Lemon and A. Zuckerman), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470987131.ch15

Editor Information

  1. 1

    Dean (Clinical) Faculty of Medicine, Imperial College, Department of Medicine, Queen Elizabeth Queen Mother Wing, St Mary's Hospital Medical School, London UK

  2. 2

    Dean of Medicine, Department of Microbiology & Immunology & Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA

  3. 3

    The Royal Free Hospital of Medicine, Rowland Hill Street, London, UK

Publication History

  1. Published Online: 26 OCT 2007
  2. Published Print: 12 JUL 2005

ISBN Information

Print ISBN: 9781405130059

Online ISBN: 9780470987131

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Keywords:

  • molecular variations;
  • core regions of hepatitis b virus;
  • polymerase chain reaction (PCR);
  • virus biology;
  • core promoter region

Summary

This chapter contains sections titled:

  • Introduction

  • Virus biology and evolution

  • Precore variants

  • Basic core promoter variants

  • Emergence of variants during chronic infection

  • Core gene variants

  • Mechanisms of emergence of variants

  • Conclusion