Chapter 17. Hepatocellular Carcinoma: Molecular Aspects in Hepatitis B

  1. Howard Thomas BSc PhD FRCP FRCpath FMedSci Professor1,
  2. Stanley Lemon Professor2 and
  3. Arie Zuckerman MD, DSc, FRCP, FRCPath, FMedSci, Dip. Bact Professor3
  1. Marie Annick Buendia,
  2. Patricia Paterlini-Bréchot,
  3. Pierre Tiollais and
  4. Christian Bréchot

Published Online: 26 OCT 2007

DOI: 10.1002/9780470987131.ch17

Viral Hepatitis, Third Edition

Viral Hepatitis, Third Edition

How to Cite

Buendia, M. A., Paterlini-Bréchot, P., Tiollais, P. and Bréchot, C. (2005) Hepatocellular Carcinoma: Molecular Aspects in Hepatitis B, in Viral Hepatitis, Third Edition (eds H. Thomas, S. Lemon and A. Zuckerman), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470987131.ch17

Editor Information

  1. 1

    Dean (Clinical) Faculty of Medicine, Imperial College, Department of Medicine, Queen Elizabeth Queen Mother Wing, St Mary's Hospital Medical School, London UK

  2. 2

    Dean of Medicine, Department of Microbiology & Immunology & Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA

  3. 3

    The Royal Free Hospital of Medicine, Rowland Hill Street, London, UK

Publication History

  1. Published Online: 26 OCT 2007
  2. Published Print: 12 JUL 2005

ISBN Information

Print ISBN: 9781405130059

Online ISBN: 9780470987131



  • hepatocellular carcinoma (HCC);
  • hepadnaviruses;
  • hepatitis B virus (HBV);
  • diabetes mellitus;
  • HBV genome


This chapter contains sections titled:

  • Epidemiological association between HBV and HCC

  • The HBV genome

  • Oncogenic properties of viral proteins

  • Viral integrations in HCC

  • HCC in HBsAg-negative patients

  • HCV and HCC

  • Genetic alterations in HBV-related HCC

  • Conclusions