Chapter 19. Pathogenesis of Chronic Hepatitis B

  1. Howard Thomas BSc PhD FRCP FRCpath FMedSci Professor1,
  2. Stanley Lemon Professor2 and
  3. Arie Zuckerman MD, DSc, FRCP, FRCPath, FMedSci, Dip. Bact Professor3
  1. Mark R Thursz and
  2. Howard C Thomas

Published Online: 26 OCT 2007

DOI: 10.1002/9780470987131.ch19

Viral Hepatitis, Third Edition

Viral Hepatitis, Third Edition

How to Cite

Thursz, M. R. and Thomas, H. C. (2005) Pathogenesis of Chronic Hepatitis B, in Viral Hepatitis, Third Edition (eds H. Thomas, S. Lemon and A. Zuckerman), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470987131.ch19

Editor Information

  1. 1

    Dean (Clinical) Faculty of Medicine, Imperial College, Department of Medicine, Queen Elizabeth Queen Mother Wing, St Mary's Hospital Medical School, London UK

  2. 2

    Dean of Medicine, Department of Microbiology & Immunology & Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA

  3. 3

    The Royal Free Hospital of Medicine, Rowland Hill Street, London, UK

Publication History

  1. Published Online: 26 OCT 2007
  2. Published Print: 12 JUL 2005

ISBN Information

Print ISBN: 9781405130059

Online ISBN: 9780470987131

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Keywords:

  • chronic hepatitis B;
  • pathogenesis;
  • adaptive immunity;
  • cytokine control;
  • viral replication

Summary

This chapter contains sections titled:

  • Introduction

  • Immunological response to HBV

  • Self-limiting infection

  • Factors leading to HBV persistence

  • How does the virus cause liver cell damage and fibrosis?

  • Summary