Chapter 1. Discovery of New Medicines

  1. John P Griffin BSc, PhD, MBBS, FRCP, FRCPath, FFPM1,
  2. John O'Grady MD, FRCP, FFPM, FBIRA, MRCPath2
  1. Anand S Dutta

Published Online: 25 OCT 2007

DOI: 10.1002/9780470987391.ch1

The Textbook of Pharmaceutical Medicine, Fifth Edition

The Textbook of Pharmaceutical Medicine, Fifth Edition

How to Cite

Dutta, A. S. (2007) Discovery of New Medicines, in The Textbook of Pharmaceutical Medicine, Fifth Edition (eds J. P. Griffin and J. O'Grady), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470987391.ch1

Editor Information

  1. 1

    Director, Asklepieion Consultancy Ltd., Visiting Professor, University of Surrey Postgraduate Medical School, Former Director, Association of the British Pharmaceutical Industry, London, Formerly Professional Head of the Medicines Division, DHSS, London

  2. 2

    Visiting Professor of Clinical Pharmacology, University of London

Publication History

  1. Published Online: 25 OCT 2007
  2. Published Print: 15 DEC 2005

ISBN Information

Print ISBN: 9780727918406

Online ISBN: 9780470987391

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Keywords:

  • bone disorders;
  • therapeutic agents;
  • metalloproteinases;
  • cyclooxygenase;
  • gene therapy

Summary

This chapter contains sections titled:

  • Introduction

  • Market Needs and Changing Disease Patterns

  • Historical Aspects

  • Impact of New Technology on Drug Discovery

  • Examples of Drug Discovery

  • Enzymes and Enzyme Inhibitors

  • Protein-Protein Interaction Inhibitors

  • Protein and Antibody Therapeutics

  • Examples of Currently Available Drugs for Major Diseases

  • Summary