Chapter 2. Genetic Mutations that Remodel the Heart in Hypertrophic Cardiomyopathy

  1. Barry J. Maron MD
  1. Carolyn Y. Ho MD and
  2. Christine E. Seidman MD

Published Online: 25 OCT 2007

DOI: 10.1002/9780470987469.ch2

Diagnosis and Management of Hypertrophic Cardiomyopathy

Diagnosis and Management of Hypertrophic Cardiomyopathy

How to Cite

Ho, C. Y. and Seidman, C. E. (2004) Genetic Mutations that Remodel the Heart in Hypertrophic Cardiomyopathy, in Diagnosis and Management of Hypertrophic Cardiomyopathy (ed B. J. Maron), Blackwell Publishing, Malden, Massachusetts, USA. doi: 10.1002/9780470987469.ch2

Editor Information

  1. Director, The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota

Publication History

  1. Published Online: 25 OCT 2007
  2. Published Print: 27 FEB 2004

ISBN Information

Print ISBN: 9781405117326

Online ISBN: 9780470987469

SEARCH

Keywords:

  • genetic mutations;
  • hypertrophic cardiomyopathy;
  • sarcomere proteins;
  • cardiac troponin T;
  • α-cardiac myosin

Summary

This chapter contains sections titled:

  • Introduction

  • Genetics of HCM

  • Mutations in sarcomere proteins define HCM

  • Genotype-phenotype correlations

  • New paradigms of inherited cardiac hypertrophy: glucose metabolism

  • Conclusions and future directions