Chapter 3. Mechanisms of Plaque Progression and Complications

  1. Raffaele De Caterina MD, PhD1,2 and
  2. Peter Libby MD3
  1. Raffaele De Caterina MD, PhD,
  2. Antonella Zampolli DBiol, PhD,
  3. Serena Del Turco DBiol, PhD and
  4. Peter Libby MD

Published Online: 12 NOV 2007

DOI: 10.1002/9780470988473.ch3

Endothelial Dysfunctions in Vascular Disease

Endothelial Dysfunctions in Vascular Disease

How to Cite

De Caterina, R., Zampolli, A., Del Turco, S. and Libby, P. (2007) Mechanisms of Plaque Progression and Complications, in Endothelial Dysfunctions in Vascular Disease (eds R. De Caterina and P. Libby), Blackwell Publishing, Oxford, UK. doi: 10.1002/9780470988473.ch3

Editor Information

  1. 1

    Professor of Cardiology, Chair and Postgraduate School of Cardiology; “G. d'Annunzio” University - Chieti, Ospedale San Camillo de Lellis; Via C. Forlanni, 50, 66100 Chieti

  2. 2

    Director, Laboratory for Thrombosis and Vascular Research; CNR Institute of Clinical Physiology, Area della Ricerca di S. Cataldo; Via G.Moruzzi, 1, 56124 Pisa, Italy

  3. 3

    Mallinckrodt Professor, Harvard Medical School and Chief, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA

Publication History

  1. Published Online: 12 NOV 2007
  2. Published Print: 1 JAN 2007

ISBN Information

Print ISBN: 9781405122085

Online ISBN: 9780470988473

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Keywords:

  • atheroma;
  • atherosclerotic lesions;
  • fatty streak;
  • lipid core;
  • plaque progression

Summary

This chapter contains sections titled:

  • General morphology of the atheroma

  • Molecular mechanisms of lesion progression

  • Mechanisms of plaque complications

  • The relationship between acute coronary syndromes and coronary anatomy as assessed from angiography - searching for the vulnerable plaque or the vulnerable patient?

  • Recent lessons and future directions