Chapter 6. High-Density Lipoprotein and Atheroprotection

  1. Raffaele De Caterina MD, PhD1,2 and
  2. Peter Libby MD3
  1. Brian Krause PhD,
  2. Reynold Homan PhD and
  3. Roger Newton PhD

Published Online: 12 NOV 2007

DOI: 10.1002/9780470988473.ch6

Endothelial Dysfunctions in Vascular Disease

Endothelial Dysfunctions in Vascular Disease

How to Cite

Krause, B., Homan, R. and Newton, R. (2007) High-Density Lipoprotein and Atheroprotection, in Endothelial Dysfunctions in Vascular Disease (eds R. De Caterina and P. Libby), Blackwell Publishing, Oxford, UK. doi: 10.1002/9780470988473.ch6

Editor Information

  1. 1

    Professor of Cardiology, Chair and Postgraduate School of Cardiology; “G. d'Annunzio” University - Chieti, Ospedale San Camillo de Lellis; Via C. Forlanni, 50, 66100 Chieti

  2. 2

    Director, Laboratory for Thrombosis and Vascular Research; CNR Institute of Clinical Physiology, Area della Ricerca di S. Cataldo; Via G.Moruzzi, 1, 56124 Pisa, Italy

  3. 3

    Mallinckrodt Professor, Harvard Medical School and Chief, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA

Publication History

  1. Published Online: 12 NOV 2007
  2. Published Print: 1 JAN 2007

ISBN Information

Print ISBN: 9781405122085

Online ISBN: 9780470988473



  • high-density lipoprotein;
  • endothelial activation;
  • chemoattractant protein-1;
  • intercellular adhesion molecule-1;
  • atheroprotection


This chapter contains sections titled:

  • Introduction

  • Inflammation

  • Oxidation pathways

  • Cholesterol uptake and efflux

  • Arterial wall “compositional” remodeling and plaque vulnerability

  • Endothelial function and signal transduction

  • Summary and future perspectives